INHIBITION OF GLUTAMINE SYNTHETASE BY PHOSPHINOTHRICIN LEADS TO TRANSCRIPTOME REPROGRAMING IN ROOT NODULES OF MEDICAGO TRUNCATULA

Inhibition of Glutamine Synthetase by Phosphinothricin Leads to Transcriptome Reprograming in Root Nodules of Medicago truncatula

Glutamine synthetase (GS) is a vital enzyme for the assimilation of ammonia into amino acids in higher plants.In legumes, GS plays a crucial role in the assimilation of the ammonium released by nitrogen-fixing bacteria in root nodules, constituting an important metabolic knob controlling the nitrogen (N) assimilatory pathways.To identify new regula

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Regulation of T cell differentiation and function by EZH2

The enhancer of zeste homologue 2 (EZH2), one of the polycomb group (PcG) proteins, is the catalytic subunit of Polycomb-repressive complex 2 (PRC2) and induces the trimethylation of Pressure Cooker the histone H3 lysine 27 (H3K27me3) promoting epigenetic gene silencing.EZH2 contains a SET domain promoting the methyltransferase activity while the t

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